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apalutamide will reduce the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medicines which might be CYP3A4 substrates can result in decreased exposure to those medications.Keep an index of the many goods you employ (suc